Tropical sprue (TS) is a syndrome characterized by acute or chronic diarrhea, weight loss, and malabsorption of nutrients. It occurs in residents. Tropical Sprue; Kwashiorkor. Sprue, both tropical and nontropical, has been a subject of great interest to the medical community ever Sp: Esprue tropical. Tropical sprue is a chronic diarrheal disease, possibly of infectious origin, that involves the small intestine and is characterized by.

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In this study, 10 of 13 patients with sprue had aerobic bacteria in the small intestine in larger numbers median 3. Trop Gastroenterol 23 — For more than a century, tropical sprue has been recognized as affecting people living in certain villages and houses sprue houses. Am J Gastroenterol 92 — Other conditions which can resemble tropical sprue need to be differentiated.

Tropical malabsorption

These may comprise using only bottled water for drinking, brushing teeth, and washing food, and avoiding fruits washed with tap water or consuming only peeled fruits, such as bananas and oranges. Am J Trop Med Hyg 10 — The need for prolonged residence in the tropics and the response to antibiotics suggested that persistent intestinal infection was responsible. Baker and Klipstein 78 suggested that the diagnosis of tropical sprue should be made only when there is malabsorption of two or more unrelated nutrient groups eg, fat and carbohydrateand after other known causes of malabsorption have been excluded.

It is now known that the condition occurs primarily in the tropics in those areas with a high rainfall, and that it affects the indigenous populations as well as Caucasians, Chinese and other immigrants. Definition Tropical sprue is a primary malabsorption syndrome that runs a chronic relapsing course. Gut 40 — N Engl J Med 87— Beet Sugar vs Cane Sugar: Key references Nath SK. A description in the ancient Indian medical treatise, Charaka samhitaof an illness characterised by chronic diarrhoea and weight loss and attributed to failure of the digestive system 1 suggests that the malabsorption syndrome was clinically recognised in the tropics two millennia ago.


Tropical sprue

Uses authors parameter Infobox medical condition new. Malabsorption is an important clinical problem in tropical countries, espruue presenting with chronic diarrhoea, glossitis, weight loss and multiple nutritional deficiencies. A villous tip accentuation of intraepithelial lymphocytosis was not appreciable in most cases. This review considers tropical malabsorption as any syndrome of malabsorption that affects indigenous residents of tropical countries and also travellers visiting or residing in the tropics.

Endoscopically, tropical sprue may resemble coeliac disease, with scalloping of the duodenal mucosa. You may improve quickly and tropicap after your first large dose of folic acid.

Tropical sprue – Wikipedia

Clinical manifestations A typical patient with tropical sprue is an adult who presents with chronic diarrhoea, glossitis, bloating, prominent bowel sounds and weight tropica. The cause of tropical sprue is not known. Tropicsl malabsorption of water and electrolytes contributes considerably to diarrhoea in patients with sprue, and may result from the action of unabsorbed bile acids and free unsaturated fatty acids.

Malabsorption of fat, vitamin B 12 and xylose, as well as increased mucosal permeability, has been noted in a large number of healthy residents of the tropics. Malabsorption can be treated by an oral dose of a pancreatic enzyme preparation such as Creon with every meal. Mucosal biopsy of the small intestine is characteristic and shows a dense cellular lymphoplasmacytic espreu in the lamina propria leading to effacement of the crypts.

Recent travel to this region is a key factor in diagnosing this disease in residents of countries espeue of that geographical region.

Nat Rev Gastroenterol Hepatol. Typically, three faecal samples should be obtained for microscopy, and examined as wet smears after concentration techniques and with special stains such as safranine methylene blue or modified AFB stains for the protozoan parasites. Both beet and cane sugar are found in many foods, including sweets and sodas. The clinician needs to consider various factors when evaluating such patients. According to tropicaal Postgraduate Medical Journalmost people show good outcomes after three to six months of treatment.


Treatment with thiabendazole, albendazole or ivermectin has been found to be effective. Tropical enteropathy and tropical sprue.

Terminal ileal resections can lead to vitamin B 12 deficiencies and espfue salt malabsorption, whereas ileocaecal valve resections result in bacterial overgrowth causing malabsorption. All content is strictly informational and should not be considered medical advice. Espprue Dis Clin North Am ; What Is Water Kefir? This article has been cited by other articles in PMC. It usually does not recur in people who get it during travel to affected regions.

The presence of Giardia cysts in the stool indicates infection. Persistent diarrhea in the returned traveler. It has become a disease of some importance in tropical warfare, as it can affect soldiers suffering from other intestinal disorders who must subsist for long periods on rations deficient in folic acid.

Tropical malabsorption

Why It Happens and How to Prevent It Since the introduction of the first birth control pill inwomen have come to rely on the pill as an effective way tdopical prevent pregnancy. A review of laboratory tests of intestinal absorption in the tropics. Kartalija M, Sande M A.

Tropical sprue is an acquired chronic diarrheal disorder of unclear etiology affecting residents of and visitors to tropical regions. In addition to expatriates residing in endemic areas for more than 1 year, the disease has affected many British and American troops and their families while previously on duty in India, Burma and the Far East.

For instance, C parvum is the most important diarrhoeal pathogen in Zaire and Uganda, whereas I belli is the most common pathogen causing chronic diarrhoea and malabsorption in south India. Tetracycline is usually not prescribed in children until they have all their permanent teeth.